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After two to three months of trying out the oral semaglutide, participants are given either active oral semaglutide or inactive placebo tablets (which look like the semaglutide tablets but have no active drug in them) for the rest of the study. This is decided by chance by a computer (like tossing a coin). This process is called randomisation. Neither the researchers nor the participants will be aware of which tablet they are taking but the study team can find out if needed.